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CDC42BPG (基因名), Serine/threonine-protein kinase MRCK gamma (蛋白名), MRCKG_HUMAN.
产品名称:

Human CDC42BPG/ Serine/threonine-protein kinase MRCK gamma Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

CDC42-binding protein kinase gamma, DMPK-like gamma, Myotonic dystrophy kinase-related CDC42-binding kinase gamma, Myotonic dystrophy protein kinase-like alpha, MRCK gamma, DMPK2

序列号:
Q6DT37
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human CDC42BPG Protein
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Human CDC42BPG Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 11q13.1 by HGNC 11q13.1 by Entrez Gene 11q13.1 by Ensembl
CDC42BPG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer and homotetramer via the coiled coil regions. Interacts tightly with GTP-bound but not GDP-bound CDC42.


功能:
May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.


亚细胞位置:
Cytoplasm Concentrates at the leading edge of cells.


该产品尚未在任何出版物中被引用。

[1].
"Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding."

[2].
"The germinal center kinase gene and a novel CDC25-like gene are located in the vicinity of the PYGM gene on 11q13."

[3].
"Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population."

[4].
"MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion."

[5].
"Architecture of the human interactome defines protein communities and disease networks."

[6].
"Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing."

[7].
"Toward a comprehensive characterization of a human cancer cell phosphoproteome."

[8].
"Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele."

[9].
"Mapping a dynamic innate immunity protein interaction network regulating type I interferon production."

[10].
"Toward a confocal subcellular atlas of the human proteome."
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