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Mrap (基因名), Melanocortin-2 receptor accessory protein (蛋白名), MRAP_MOUSE.
产品名称:

Mouse Mrap/ Melanocortin-2 receptor accessory protein Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Fat cell-specific low molecular weight protein, Fat tissue-specific low MW protein, Falp

序列号:
Q9D159
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Mrap Protein
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Mouse Mrap Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Homodimer and heterodimer. Forms antiparallel homodimers and heterodimers with MRAP2. Interacts with MC1R, MC2R, MC3R, MC4R and MC5R.


功能:
Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.


亚细胞位置:
Cell membrane Single-pass membrane protein Endoplasmic reticulum membrane Single-pass membrane protein The formation of antiparallel homo- and heterodimers suggest that N- and C-terminus can both localize in the cytoplasmic and extracellular parts, depending on the context. Upon insulin stimulation, it is redistributed into spotty structures throughout the cytoplasm (By similarity).


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