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MPZL1 (基因名), Myelin protein zero-like protein 1 (蛋白名), MPZL1_HUMAN.
产品名称:

Human MPZL1/ Myelin protein zero-like protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Protein zero-related, UNQ849/PRO1787, PZR

序列号:
O95297
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MPZL1 Protein
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Human MPZL1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 1q24.2 by HGNC 1q24.2 by Entrez Gene 1q24.2 by Ensembl
MPZL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with phosphorylated PTPN11/SHP-2.


功能:
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.


亚细胞位置:
Membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs."

[2].
"Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration."

[3].
"Purification and cloning of PZR, a binding protein and putative physiological substrate of tyrosine phosphatase SHP-2."

[4].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[5].
"Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation."

[6].
"Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study."

[7].
"The DNA sequence and biological annotation of human chromosome 1."

[8].
"MPZL1/PZR, a novel candidate predisposing schizophrenia in Han Chinese."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
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