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Mprip (基因名), Myosin phosphatase Rho-interacting protein (蛋白名), MPRIP_MOUSE.
产品名称:

Mouse Mprip/ Myosin phosphatase Rho-interacting protein Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Rho-interacting protein 3, p116Rip, RIP3, Kiaa0864, Mrip, Rhoip3

序列号:
P97434
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Mprip Protein
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Mouse Mprip Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Binds RHOA, PPP1R12A/MBS and PPP1R12C/MBS85 through adjacent coiled coil domains. Interacts with MYZAP. Binds F-actin through its N-terminus.


功能:
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.


亚细胞位置:
Cytoplasm Cytoskeleton Colocalizes with F-actin.


该产品尚未在任何出版物中被引用。
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