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MPPE1 (基因名), Metallophosphoesterase 1 (蛋白名), MPPE1_HUMAN.
产品名称:

Human MPPE1/ Metallophosphoesterase 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Post-GPI attachment to proteins factor 5, PP579, PGAP5

序列号:
Q53F39
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MPPE1 Protein
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Human MPPE1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 18p11.21 by HGNC 18p11.21 by Entrez Gene 18p11.21 by Ensembl
MPPE1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with GPI-anchor proteins. Interacts with TMED10.


功能:
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.


亚细胞位置:
Endoplasmic reticulum-Golgi intermediate compartment membrane Multi-pass membrane protein Golgi apparatus Cis-Golgi network membrane Multi-pass membrane protein Also localizes to endoplasmic reticulum exit site.


该产品尚未在任何出版物中被引用。

[1].
"Association between polymorphisms in the metallophosphoesterase (MPPE1) gene and bipolar disorder."

[2].
"GPI glycan remodeling by PGAP5 regulates transport of GPI-anchored proteins from the ER to the Golgi."

[3].
"cDNA cloning, genomic organization and expression of the novel human metallophosphoesterase gene MPPE1 on chromosome 18p11.2."

[4].
"Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population."

[5].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."

[8].
"A proteome-scale map of the human interactome network."

[9].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."

[10].
"The structure and function of a novel glycerophosphodiesterase from Enterobacter aerogenes."
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