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Mpp5 (基因名), MAGUK p55 subfamily member 5 (蛋白名), MPP5_MOUSE.
产品名称:

Mouse Mpp5/ MAGUK p55 subfamily member 5 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Protein associated with Lin-7 1, Pals1

序列号:
Q9JLB2
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Mpp5 Protein
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Mouse Mpp5 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Heterodimer with MPP1. Interacts with MPP7. Forms a complex with CRB1 and MPP4. Component of a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, PATJ and PARD3/PAR3 (By similarity). Interacts with CRB3, EZR, PATJ, LIN7C, MPDZ, PARD6B and SC6A1.


功能:
May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton.


亚细胞位置:
Cell membrane Peripheral membrane protein Endomembrane system Peripheral membrane protein Cell junction Tight junction Localized to the tight junctions of epithelial cells and a subset of intracellular vesicles. Localized to the Purkinje cell body and axon. Localized to apical membrane domains of the outer limiting membrane junctions in the retina. Colocalizes with MPP1 in the retina at the outer limiting membrane (OLM) (By similarity).


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