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CDC25C (基因名), M-phase inducer phosphatase 3 (蛋白名), MPIP3_HUMAN.
产品名称:

Human CDC25C/ M-phase inducer phosphatase 3 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Dual specificity phosphatase Cdc25C

序列号:
P30307
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human CDC25C Protein
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Human CDC25C Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 5q31.2 by HGNC 5q31.2 by Entrez Gene 5q31.2 by Ensembl
CDC25C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with HIV-1 Vpr, thereby inactivating CDC25C phosphatase activity. Interacts with MAPK14 and 14-3-3 proteins. When phosphorylated on Ser-129 and/or Thr-130, interacts with PLK1.


功能:
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。

[1].
"Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation."

[2].
"The human immunodeficiency virus Vpr protein binds Cdc25C: implications for G2 arrest."

[3].
"Alternative splicing in the regulatory region of the human phosphatases CDC25A and CDC25C."

[4].
"An additional transcript of the cdc25C gene from A431 cells encodes a functional protein."

[5].
"The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase."
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