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Mpdz (基因名), Multiple PDZ domain protein (蛋白名), MPDZ_RAT.
产品名称:

Rat Mpdz/ Multiple PDZ domain protein Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Multi-PDZ domain protein 1, Mupp1

序列号:
O55164
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Mpdz Protein
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Rat Mpdz Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Interacts with F11R/JAM, CLDN1, NG2, CXADR, CRB1, MPP4 and MPP5, HTR2A, HTR2B, PLEKHA1/TAPP1 and PLEKHA2/TAPP2. Interacts with CXADR (By similarity). Interacts with HTR2C, CLDN5, DLG4, GRIN1, SYNGAP1, CAMK2A and CAMK2B. Interacts with FAT4 (via cytoplasmic domain) (By similarity). Interacts with the adenovirus type 9 E4-ORF1 protein and the HPV18 E6 protein. Interacts with DLL1.


功能:
Interacts with HTR2C and provokes its clustering at the cell surface. Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.


亚细胞位置:
Endomembrane system Cell junction Tight junction Cell junction Synapse Apical cell membrane Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell projection Dendrite Cell junction Synapse Synaptosome Associated with membranes. Enriched at the tight junctions of epithelial cells. Association to the tight junctions depends on CXADR. In the retina, localizes to the sub-apical region adjacent to the adherens junction complex at the outer limiting membrane (By similarity). Colocalizes with HTR2C on the apical membrane of epithelial choroid plexus cells. Localized mainly in the Schmidt-Lanterman incisures of myelinating Schwann cells. Highly enriched in postsynaptic densities (PSD). Localized to punctae on dendrites of hippocampal neurons and colocalizes with the synaptic marker DLG4.


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