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MAP2K5 (基因名), Dual specificity mitogen-activated protein kinase kinase 5 (蛋白名), MP2K5_HUMAN.
产品名称:

Human MAP2K5/ Dual specificity mitogen-activated protein kinase kinase 5 Recombinant Protein
双特异性促分裂原活化蛋白激酶激酶5

货号:

R10343h

商标:
EIAab®
监管等级:
别名:

MAPK/ERK kinase 5, MEK 5, MAP kinase kinase 5, MEK5, MKK5, PRKMK5

序列号:
Q13163
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human MAP2K5 Protein
规格 & 价格: cart
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Human MAP2K5 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 15q23 by HGNC 15q23 by Entrez Gene 15q23 by Ensembl
MAP2K5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with PARD6A, MAP3K3 and MAPK7. Forms a complex with SQSTM1 and PRKCZ or PRKCI (By similarity). Interacts with Yersinia yopJ.


功能:
Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Components of a new human protein kinase signal transduction pathway."

[2].
"Meta-analysis identifies common variants associated with body mass index in east Asians."

[3].
"Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1."

[4].
"PB1 domain interaction of p62/sequestosome 1 and MEKK3 regulates NF-kappaB activation."

[5].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
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