MINOS1 (基因名), Mitochondrial inner membrane organizing system protein 1 (蛋白名), MOS1_HUMAN.
Human MINOS1/ Mitochondrial inner membrane organizing system protein 1 Recombinant Protein
>90% by SDS-PAGE
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50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
Store at -20°C. (Avoid repeated freezing and thawing.)
Component of the MINOS/MitOS complex, that includes IMMT, HSPA9 and CHCHD3 and associates with mitochondrial outer membrane proteins SAMM50, MTX1 and MTX2.
May play a role in mitochondrial architecture.
Mitochondrion inner membrane Single-pass membrane protein The C-terminus is located in the intermembrane space (By similarity), while the location of the N-terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space.
"The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions."
"Uniform nomenclature for the mitochondrial contact site and cristae organizing system."
"MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization."
"Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis."
"The DNA sequence and biological annotation of human chromosome 1."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
"Mapping the Genetic Landscape of Human Cells."
"Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing."
"RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination."
"Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt."
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