MRFAP1 (基因名), MORF4 family-associated protein 1 (蛋白名), MOFA1_HUMAN.
Human MRFAP1/ MORF4 family-associated protein 1 Recombinant Protein
Protein PGR1, Protein associated with MRG of 14 kDa, PAM14, PGR1
>90% by SDS-PAGE
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50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
Store at -20°C. (Avoid repeated freezing and thawing.)
Found in a complex composed of MORF4L1, MRFAP1 and RB1. Interacts via its N-terminus with MORF4L1. Interacts with CSTB and MORF4L2.
Nucleus Cytoplasm Perinuclear region Colocalizes with MORF4L1 to cell nuclei.
"The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14."
"PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice."
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
"MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner."
"MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation."
"MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14."
"Architecture of the human interactome defines protein communities and disease networks."
"Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways."
"Pooled-matrix protein interaction screens using Barcode Fusion Genetics."
"Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes."
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