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MSN (基因名), Moesin (蛋白名), MOES_HUMAN.
产品名称:

Human MSN/ Moesin Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Membrane-organizing extension spike protein

序列号:
P26038
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MSN Protein
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Human MSN Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: Xq12 by HGNC Xq12 by Entrez Gene Xq12 by Ensembl
MSN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation (By similarity). Binds SLC9A3R1. Interacts with PPP1R16B. Interacts with PDZD8. Interacts with SELPLG and SYK; mediates the activation of SYK by SELPLG.


功能:
Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.


亚细胞位置:
Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm Cytoskeleton Apical cell membrane Peripheral membrane protein Cytoplasmic side Cell projection Microvillus membrane Peripheral membrane protein Cytoplasmic side Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment.


该产品尚未在任何出版物中被引用。

[1].
"Moesin: a member of the protein 4.1-talin-ezrin family of proteins."

[2].
"TIMAP is a positive regulator of pulmonary endothelial barrier function."

[3].
"ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1."

[4].
"Subcellular localization of moesin in dynamic filopodia, retraction fibers, and other structures involved in substrate exploration, attachment, and cell-cell contacts."

[5].
"X-linked primary immunodeficiency associated with hemizygous mutations in the moesin (MSN) gene."
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