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MNT (基因名), Max-binding protein MNT (蛋白名), MNT_HUMAN.
产品名称:

Human MNT/ Max-binding protein MNT Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Class D basic helix-loop-helix protein 3, Myc antagonist MNT, Protein ROX, bHLHd3, BHLHD3, ROX

序列号:
Q99583
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MNT Protein
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Human MNT Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 17p13.3 by HGNC 17p13.3 by Entrez Gene 17p13.3 by Ensembl
MNT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a homodimer or a heterodimer with MAX.


功能:
Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。

[1].
"The human ROX gene: genomic structure and mutation analysis in human breast tumors."

[2].
"Switch from Mnt-Max to Myc-Max induces p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes."

[3].
"Mnt takes control as key regulator of the myc/max/mxd network."

[4].
"Expression and mutation analysis of genes that encode the Myc antagonists Mad1, Mxi1 and Rox in acute leukaemia."

[5].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[6].
"Expression and DNA-binding activity of MYCN/Max and Mnt/Max during induced differentiation of human neuroblastoma cells."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?"

[9].
"Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor."

[10].
"Architecture of the human interactome defines protein communities and disease networks."
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