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MNDA (基因名), Myeloid cell nuclear differentiation antigen (蛋白名), MNDA_HUMAN.
产品名称:

Human MNDA/ Myeloid cell nuclear differentiation antigen Recombinant Protein
髓细胞核分化抗原

货号:

R1775h

商标:
EIAab®
监管等级:
序列号:
P41218
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human MNDA Protein
规格 & 价格: cart
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Human MNDA Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q23.1 by HGNC 1q23.1 by Entrez Gene 1q23.1 by Ensembl
MNDA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Participates in a ternary complex with YY1 and the YY1 target DNA element. Binds nucleolin and nucleophosmin/NPM/B23.


功能:
May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.


亚细胞位置:
Nucleus Cytoplasm Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.


该产品尚未在任何出版物中被引用。

[1].
"The human myeloid cell nuclear differentiation antigen gene is one of at least two related interferon-inducible genes located on chromosome 1q that are expressed specifically in hematopoietic cells."

[2].
"Cloning and expression of the human myeloid cell nuclear differentiation antigen: regulation by interferon alpha."

[3].
"Human hematopoietic cell specific nuclear protein MNDA interacts with the multifunctional transcription factor YY1 and stimulates YY1 DNA binding."

[4].
"The closely linked genes encoding the myeloid nuclear differentiation antigen (MNDA) and IFI16 exhibit contrasting haemopoietic expression."

[5].
"Interferon alpha selectively affects expression of the human myeloid cell nuclear differentiation antigen in late stage cells in the monocytic but not the granulocytic lineage."

[6].
"Characterization of the human myeloid cell nuclear differentiation antigen: relationship to interferon-inducible proteins."

[7].
"The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA."

[8].
"Association of IFI200 gene polymorphisms with susceptibility to systemic lupus erythematosus."

[9].
"Identification of MNDA as a new marker for nodal marginal zone lymphoma."

[10].
"ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia."
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