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MMS22L (基因名), Protein MMS22-like (蛋白名), MMS22_HUMAN.
产品名称:

Human MMS22L/ Protein MMS22-like Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Methyl methanesulfonate-sensitivity protein 22-like, C6orf167

序列号:
Q6ZRQ5
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MMS22L Protein
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Human MMS22L Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 6q16.1 by HGNC 6q16.1 by Entrez Gene 6q16.1 by Ensembl
MMS22L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Component of the MMS22L-TONSL complex, a complex at least composed of MMS22L and TONSL/NFKBIL2.


功能:
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA.


亚细胞位置:
Nucleus Localizes to DNA damage sites, accumulates at stressed replication forks.


该产品尚未在任何出版物中被引用。

[1].
"The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination."

[2].
"Identification of the MMS22L-TONSL complex that promotes homologous recombination."

[3].
"A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability."

[4].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[5].
"The DNA sequence and analysis of human chromosome 6."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model."

[8].
"H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex."

[9].
"The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress."

[10].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."
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