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Mmp24 (基因名), Matrix metalloproteinase-24 (蛋白名), MMP24_RAT.
产品名称:

Rat Mmp24/ Matrix metalloproteinase-24 Recombinant Protein
矩阵metalloproteinase-24

货号:

R0555r

商标:
EIAab®
监管等级:
别名:

Membrane-type matrix metalloproteinase 5, Membrane-type-5 matrix metalloproteinase, MT-MMP 5, MT5-MMP, MMP-24, Mt5mmp

序列号:
Q99PW6
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Mmp24 Protein
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Rat Mmp24 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts (via PDZ-binding motif) with APBA3 (via PDZ domain) (By similarity). Interacts with GRIP1 and GRIP2.


功能:
Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin.


亚细胞位置:
Processed matrix metalloproteinase-24 Secreted Extracellular space Extracellular matrix Also shed from cell surface as soluble proteinase, by a proteolytic cleavage.


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