首页 > 重组蛋白 > Human MMP24 Recombinant Protein

MMP24 (基因名), Matrix metalloproteinase-24 (蛋白名), MMP24_HUMAN.

产品名称:

Human MMP24/ Matrix metalloproteinase-24 Recombinant Protein
矩阵metalloproteinase-24

货号:

R0555h

商标:

EIAab^®

监管等级:

RUO

别名:

Membrane-type matrix metalloproteinase 5, Membrane-type-5 matrix metalloproteinase, MT-MMP 5, MT5-MMP, MMP-24, MT5MMP

序列号:

Q9Y5R2

来源:

E.coli

种属:

Human

标签:

His

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human MMP24 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 20q11.22 by HGNC 20q11.22 by Entrez Gene 20q11.22 by Ensembl

MMP24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Interacts (via PDZ-binding motif) with APBA3 (via PDZ domain). Interacts with GRIP1 and GRIP2.

功能:

Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin.

亚细胞位置:

Processed matrix metalloproteinase-24 Secreted Extracellular space Extracellular matrix Also shed from cell surface as soluble proteinase, by a proteolytic cleavage.

数据库链接

UniGene:

Hs.715494

SMR:

Q9Y5R2

STRING:

9606.ENSP00000246186

KEGG:

hsa:10893

MIM:

604871

Pfam:

PF11857

Uniprot:

Q9Y5R2

相关产品

Mouse Mmp24 ELISA Kit

序列长度:

645

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

645:

NAVAVVIPCI | LSLCILVLVY | TIFQFKNKTG | PQPVTYYKRP | VQEWV

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Identification and characterization of human MT5-MMP, a new membrane-bound activator of progelatinase a overexpressed in brain tumors."

(PMID: 10363975)

[2].

"Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection."

(PMID: 20587546)

[3].

"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

(PMID: 20628086)

[4].

"The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature."

(PMID: 20546612)

[5].

"Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies."

(PMID: 18839057)

[6].

"Many sequence variants affecting diversity of adult human height."

(PMID: 18391951)

[7].

"Expression of membrane-type 5 matrix metalloproteinase in human endometrium and endometriosis."

(PMID: 17952761)

[8].

"Identification of a novel human MT5-MMP transcript variant in multipotent NT2 cells."

(PMID: 18062926)

[9].

"Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases."

(PMID: 12879005)

[10].

"The DNA sequence and comparative analysis of human chromosome 20."

(PMID: 11780052)

[1].

人矩阵metalloproteinase-24(MMP24)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人矩阵metalloproteinase-24(MMP24)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人矩阵metalloproteinase-24(MMP24)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人矩阵metalloproteinase-24(MMP24)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人矩阵metalloproteinase-24(MMP24)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人矩阵metalloproteinase-24(MMP24)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人矩阵metalloproteinase-24(MMP24)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人矩阵metalloproteinase-24(MMP24)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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