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MMP17 (基因名), Matrix metalloproteinase-17 (蛋白名), MMP17_HUMAN.
产品名称:

Human MMP17/ Matrix metalloproteinase-17 Recombinant Protein
基质金属蛋白酶17

货号:

R0554h

商标:
EIAab®
监管等级:
别名:

Membrane-type matrix metalloproteinase 4, Membrane-type-4 matrix metalloproteinase, MT-MMP 4, MT4-MMP, MMP-17, MT4MMP

序列号:
Q9ULZ9
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MMP17 Protein
规格 & 价格: cart
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Human MMP17 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 12q24.33 by HGNC 12q24.33 by Entrez Gene 12q24.33 by Ensembl
MMP17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.


亚细胞位置:
Isoform Long Cell membrane Lipid-anchor GPI-anchor Extracellular side Secreted Extracellular space Extracellular matrix


该产品尚未在任何出版物中被引用。

[1].
"Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts."

[2].
"Membrane type 4 matrix metalloproteinase (MT4-MMP, MMP-17) is a glycosylphosphatidylinositol-anchored proteinase."

[3].
"Localization of the human membrane type 4-matrix metalloproteinase gene (MMP17) to chromosome 12q24."

[4].
"Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma."

[5].
"Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes."

[6].
"Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection."

[7].
"A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)."

[8].
"Membrane-type 4 matrix metalloproteinase (MT4-MMP) induces lung metastasis by alteration of primary breast tumour vascular architecture."

[9].
"Regulation of membrane-type 4 matrix metalloproteinase by SLUG contributes to hypoxia-mediated metastasis."

[10].
"MT1-MMP hemopexin domain exchange with MT4-MMP blocks enzyme maturation and trafficking to the plasma membrane in MCF7 cells."
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