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Myl2 (基因名), Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (蛋白名), MLRV_RAT.
产品名称:

Rat Myl2/ Myosin regulatory light chain 2, ventricular/cardiac muscle isoform Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Myosin light chain 2, slow skeletal/ventricular muscle isoform, MLC-2s/v, MLC-2, Mlc2

序列号:
P08733
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Myl2 Protein
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Rat Myl2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


通用注释


亚单元:
Myosin is a hexamer of 2 heavy chains and 4 light chains (By similarity). Interacts with MYOC.


功能:
Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (PubMed:15331360). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly.


亚细胞位置:
Cytoplasm Myofibril Sarcomere A band


该产品尚未在任何出版物中被引用。
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