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MAP1LC3C (基因名), Microtubule-associated proteins 1A/1B light chain 3C (蛋白名), MLP3C_HUMAN.
产品名称:

Human MAP1LC3C/ Microtubule-associated proteins 1A/1B light chain 3C Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Autophagy-related protein LC3 C, Autophagy-related ubiquitin-like modifier LC3 C, MAP1 light chain 3-like protein 3, MAP1A/MAP1B light chain 3 C, Microtubule-associated protein 1 light chain 3 gamma, MAP1A/MAP1B LC3 C

序列号:
Q9BXW4
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human MAP1LC3C Protein
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Human MAP1LC3C Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 1q43 by HGNC 1q43 by Entrez Gene 1q43 by Ensembl
MAP1LC3C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins (By similarity). Interacts with TP53INP1 and TP53INP2. Interacts with CALCOCO2. Interacts with TECPR2. Interacts with TBC1D5 (PubMed:22354992). Found in a complex with UBQLN1 and UBQLN2 (PubMed:20529957). Interacts with UBQLN4 (via STI1 1 and 2 domains). Interacts with UBQLN1 in the presence of UBQLN4 (PubMed:23459205). Interacts with TRIM5 (PubMed:25127057). Interacts with ATG13 (PubMed:24290141). Interacts with MEFV and TRIM21 (PubMed:26347139).


功能:
Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium.


亚细胞位置:
Cytoplasm Cytoskeleton Endomembrane system Lipid-anchor Cytoplasmic vesicle Autophagosome membrane Lipid-anchor Cytoplasmic vesicle Autophagosome LC3-II binds to the autophagic membranes.


该产品尚未在任何出版物中被引用。

[1].
"Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B."

[2].
"The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy."

[3].
"TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity."

[4].
"Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism."

[5].
"TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition."

[6].
"Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery."

[7].
"Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers."

[8].
"DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription."

[9].
"LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy."

[10].
"Network organization of the human autophagy system."
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