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MLIP (基因名), Muscular LMNA-interacting protein (蛋白名), MLIP_HUMAN.
产品名称:

Human MLIP/ Muscular LMNA-interacting protein Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Cardiac Isl1-interacting protein, Muscular-enriched A-type laminin-interacting protein, CIP, C6orf142, Cip

序列号:
Q5VWP3
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MLIP Protein
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Human MLIP Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 6p12.1 by HGNC 6p12.1 by Entrez Gene 6p12.1 by Ensembl
MLIP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with LMNA (PubMed:21498514). Interacts with ISL1 (via N-terminal domain); the interaction represses ISL1 transactivator activity (By similarity).


功能:
Required for precocious cardiac adaptation to stress through integrated regulation of the AKT/mTOR pathways and FOXO1. Regulates cardiac homeostasis and plays an important role in protection against cardiac hypertrophy. Acts as a transcriptional cofactor, represses transactivator activity of ISL1 and MYOCD.


亚细胞位置:
Nucleus Nucleus envelope Nucleus PML body Cell membrane Sarcolemma Peripheral membrane protein Cytoplasmic side


该产品尚未在任何出版物中被引用。

[1].
"Identification of a novel muscle A-type lamin-interacting protein (MLIP)."

[2].
"Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis."

[3].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[4].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[5].
"The DNA sequence and analysis of human chromosome 6."
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