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Mink1 (基因名), Misshapen-like kinase 1 (蛋白名), MINK1_RAT.
产品名称:

Rat Mink1/ Misshapen-like kinase 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

GCK family kinase MiNK, MAPK/ERK kinase kinase kinase 6, Misshapen/NIK-related kinase, Mitogen-activated protein kinase kinase kinase kinase 6, MEK kinase kinase 6, Map4k6, Mink

序列号:
F1LP90
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Mink1 Protein
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Rat Mink1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Interacts with RAP2A and NCK1 (By similarity). Interacts with TANC1.


功能:
Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.


亚细胞位置:
Cytoplasm Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell projection Axon Cell projection Dendrite


该产品尚未在任何出版物中被引用。
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