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MIER1 (基因名), Mesoderm induction early response protein 1 (蛋白名), MIER1_HUMAN.
产品名称:

Human MIER1/ Mesoderm induction early response protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Early response 1, KIAA1610

序列号:
Q8N108
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MIER1 Protein
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Human MIER1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 1p31.3 by HGNC 1p31.3 by Entrez Gene 1p31.3 by Ensembl
MIER1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with HDAC1. Part of a complex containing at least CDYL, MIER1, MIER2, HDAC1 and HDAC2.


功能:
Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing.


亚细胞位置:
Isoform 6 Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Genomic organization of the human mi-er1 gene and characterization of alternatively spliced isoforms: regulated use of a facultative intron determines subcellular localization."

[2].
"Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain."

[3].
"The DNA sequence and biological annotation of human chromosome 1."

[4].
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."

[5].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[6].
"The SANT domain of human MI-ER1 interacts with Sp1 to interfere with GC box recognition and repress transcription from its own promoter."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

[9].
"Molecular cloning of human er1 cDNA and its differential expression in breast tumours and tumour-derived cell lines."

[10].
"A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome."
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