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MIEF2 (基因名), Mitochondrial dynamics protein MID49 (蛋白名), MID49_HUMAN.
产品名称:

Human MIEF2/ Mitochondrial dynamics protein MID49 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Mitochondrial dynamics protein of 49 kDa, Mitochondrial elongation factor 2, Smith-Magenis syndrome chromosomal region candidate gene 7 protein, MID49, SMCR7

序列号:
Q96C03
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MIEF2 Protein
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Human MIEF2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 17p11.2 by HGNC 17p11.2 by Entrez Gene 17p11.2 by Ensembl
MIEF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with DNM1L.


功能:
Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity.


亚细胞位置:
Mitochondrion outer membrane Single-pass membrane protein Colocalizes with DNM1L at mitochondrial membrane. Forms foci and rings around mitochondria.


该产品尚未在任何出版物中被引用。

[1].
"MiD49 and MiD51, new components of the mitochondrial fission machinery."

[2].
"Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse."

[3].
"Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission."

[4].
"Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission."

[5].
"Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"Foxo3a inhibits mitochondrial fission and protects against doxorubicin-induced cardiotoxicity by suppressing MIEF2."

[8].
"Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling."

[9].
"The role of Drp1 adaptor proteins MiD49 and MiD51?in mitochondrial fission: implications for human disease."

[10].
"Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein."
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