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Mia2 (基因名), Melanoma inhibitory activity protein 2 (蛋白名), MIA2_MOUSE.
产品名称:

Mouse Mia2/ Melanoma inhibitory activity protein 2 Recombinant Protein
黑色素瘤活性抑制蛋白2

货号:

R13472m

商标:
EIAab®
监管等级:
别名:

CTAGE family member 5 ER export factor, Ctage5

序列号:
Q91ZV0
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Mouse Mia2 Protein
规格 & 价格: cart
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Mouse Mia2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with MIA3 (By similarity). Interacts with the COPII coat subunits SEC23A, SEC23B and maybe SEC24C (By similarity) (PubMed:21807889). Interacts with PREB; recruits PREB to endoplasmic reticulum exit sites. Interacts with APOB (By similarity).


功能:
Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (By similarity). Thereby, may play a role in cholesterol and triglyceride homeostasis (PubMed:21807889). Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites (By similarity).


亚细胞位置:
Endoplasmic reticulum membrane Single-pass membrane protein Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).


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