首页 > 重组蛋白 > Human MIA2 Recombinant Protein

MIA2 (基因名), Melanoma inhibitory activity protein 2 (蛋白名), MIA2_HUMAN.

产品名称:

Human MIA2/ Melanoma inhibitory activity protein 2 Recombinant Protein
黑色素瘤活性抑制蛋白2

货号:

R13472h

商标:

EIAab^®

监管等级:

RUO

别名:

CTAGE family member 5 ER export factor, Meningioma-expressed antigen 6/11, CTAGE5, MEA11, MEA6, MGEA11, MGEA6

序列号:

Q96PC5

来源:

E.coli

种属:

Human

标签:

His

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

Cancer

规格 & 价格:

关注

Human MIA2 Protein

邮箱 *

消息 *

Please 登录.

产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
反馈墙 (0)

R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 14q13.2 by HGNC 14q13.2 by Entrez Gene 14q13.2 by Ensembl

MIA2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Interacts with MIA3 (PubMed:21525241, PubMed:25202031, PubMed:27138255, PubMed:27170179). Interacts with the COPII coat subunits SEC23A, SEC23B and maybe SEC24C (PubMed:21525241, PubMed:27551091). Interacts with PREB; recruits PREB to endoplasmic reticulum exit sites (PubMed:25202031, PubMed:27170179). Interacts with APOB (PubMed:27138255).

功能:

Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum (PubMed:27138255, PubMed:21525241, PubMed:25202031, PubMed:27170179). Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum (PubMed:27138255). Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity). Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PREB/SEC12 at the endoplasmic reticulum exit sites (PubMed:21525241, PubMed:25202031, PubMed:27170179).

亚细胞位置:

Endoplasmic reticulum membrane Single-pass membrane protein Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).

数据库链接

UniGene:

Hs.287694

SMR:

Q96PC5

STRING:

9606.ENSP00000280082

MIM:

608001

Pfam:

PF07653

Uniprot:

Q96PC5

相关产品

Mouse Mia2 ELISA Kit

Mouse Mia2 CLIA Kit

Mouse Mia2 Protein

Mouse Mia2 Polyclonal Antibody

Mouse Mia2 Monoclonal Antibody

序列长度:

1412

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1400:

1435:

PP PPHSEGR | SEFPSGLIPP | SNEPATEHPE | PQQET

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum."

(PMID: 27138255)

[2].

"Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes."

(PMID: 12586826)

[3].

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."

(PMID: 24275569)

[4].

"Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites."

(PMID: 21807889)

[5].

"The consensus coding sequences of human breast and colorectal cancers."

(PMID: 16959974)

[6].

"Complete sequencing and characterization of 21,243 full-length human cDNAs."

(PMID: 14702039)

[7].

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

(PMID: 15489334)

[8].

"The DNA sequence and analysis of human chromosome 14."

(PMID: 12508121)

[9].

"MGEA6 is tumor-specific overexpressed and frequently recognized by patient-serum antibodies."

(PMID: 11803467)

[10].

"Architecture of the human interactome defines protein communities and disease networks."

(PMID: 28514442)

[1].

人黑色素瘤活性抑制蛋白2(MIA2)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人黑色素瘤活性抑制蛋白2(MIA2)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人黑色素瘤活性抑制蛋白2(MIA2)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人黑色素瘤活性抑制蛋白2(MIA2)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人黑色素瘤活性抑制蛋白2(MIA2)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人黑色素瘤活性抑制蛋白2(MIA2)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人黑色素瘤活性抑制蛋白2(MIA2)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人黑色素瘤活性抑制蛋白2(MIA2)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

反馈墙

评论数 : 0

所有用户