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MGAT5B (基因名), Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B (蛋白名), MGT5B_HUMAN.
产品名称:

Human MGAT5B/ Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Alpha-mannoside beta-1, 6-N-acetylglucosaminyltransferase B, GlcNAc-T Vb, Mannoside acetylglucosaminyltransferase 5B, N-acetylglucosaminyl-transferase Vb, N-acetylglucosaminyltransferase IX, GNT-Vb, GNT-IX, KIAA2008

序列号:
Q3V5L5
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MGAT5B Protein
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Human MGAT5B Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 17q25.2 by HGNC 17q25.2 by Entrez Gene 17q25.2 by Ensembl
MGAT5B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.


亚细胞位置:
Golgi apparatus membrane Single-pass type II membrane protein


该产品尚未在任何出版物中被引用。

[1].
"N-Acetylglucosaminyltransferase IX acts on the GlcNAc beta 1,2-Man alpha 1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan."

[2].
"A novel beta(1,6)-N-acetylglucosaminyltransferase V (GnT-VB)(1)."

[3].
"Comparison of the substrate specificities and catalytic properties of the sister N-acetylglucosaminyltransferases, GnT-V and GnT-Vb (IX)."

[4].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[5].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[6].
"Demonstration of the expression and the enzymatic activity of N-acetylglucosaminyltransferase IX in the mouse brain."

[7].
"N-acetylglucosaminyltranferase VB expression enhances beta1 integrin- dependent PC12 neurite outgrowth on laminin and collagen."

[8].
"Integrin-dependent neuroblastoma cell adhesion and migration on laminin is regulated by expression levels of two enzymes in the O-mannosyl-linked glycosylation pathway, PomGnT1 and GnT-Vb."

[9].
"Molecular cloning and characterization of human GnT-IX, a novel beta1,6-N-acetylglucosaminyltransferase that is specifically expressed in the brain."

[10].
"Architecture of the human interactome defines protein communities and disease networks."
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