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MGAT4B (基因名), Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (蛋白名), MGT4B_HUMAN.
产品名称:

Human MGAT4B/ Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb, UDP-N-acetylglucosamine: alpha-1, 3-D-mannoside beta-1, 4-N-acetylglucosaminyltransferase IVb, GlcNAc-T IVb, UNQ906/PRO1927

序列号:
Q9UQ53
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MGAT4B Protein
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Human MGAT4B Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 5q35.3 by HGNC 5q35.3 by Entrez Gene 5q35.3 by Ensembl
MGAT4B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.


亚细胞位置:
Golgi apparatus membrane Single-pass type II membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes."

[2].
"A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment."

[3].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[4].
"N-glycan alterations are associated with drug resistance in human hepatocellular carcinoma."

[5].
"Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."

[8].
"Architecture of the human interactome defines protein communities and disease networks."

[9].
"UDP-galactose (SLC35A2) and UDP-N-acetylglucosamine (SLC35A3) Transporters Form Glycosylation-related Complexes with Mannoside Acetylglucosaminyltransferases (Mgats)."

[10].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."
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