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MGAT2 (基因名), Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (蛋白名), MGAT2_HUMAN.
产品名称:

Human MGAT2/ Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Beta-1, 2-N-acetylglucosaminyltransferase II, GlcNAc-T II, Mannoside acetylglucosaminyltransferase 2, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II, GNT-II

序列号:
Q10469
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MGAT2 Protein
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Human MGAT2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 14q21.3 by HGNC 14q21.3 by Entrez Gene 14q21.3 by Ensembl
MGAT2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans.


亚细胞位置:
Golgi apparatus membrane Single-pass type II membrane protein


该产品尚未在任何出版物中被引用。

[1].
"The human UDP-N-acetylglucosamine: alpha-6-D-mannoside-beta-1,2- N-acetylglucosaminyltransferase II gene (MGAT2). Cloning of genomic DNA, localization to chromosome 14q21, expression in insect cells and purification of the recombinant protein."

[2].
"Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development."

[3].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[4].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[5].
"Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis."

[6].
"Congenital disorders of glycosylation IIa cause growth retardation, mental retardation, and facial dysmorphism."

[7].
"Transcriptional regulation of the human UDP-GlcNAc:alpha-6-D-mannoside beta-1-2-N-acetylglucosaminyltransferase II gene (MGAT2) which controls complex N-glycan synthesis."

[8].
"Molecular cloning and expression of cDNA encoding the rat UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II."

[9].
"Human N-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite."

[10].
"Heterologous expression, purification and characterization of human β-1,2-N-acetylglucosaminyltransferase II using a silkworm-based Bombyx mori nucleopolyhedrovirus bacmid expression system."
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