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MFF (基因名), Mitochondrial fission factor (蛋白名), MFF_HUMAN.
产品名称:

Human MFF/ Mitochondrial fission factor Recombinant Protein

货号:

R15962h

商标:
EIAab®
监管等级:
别名:

AD030, AD033, GL004, C2orf33

序列号:
Q9GZY8
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human MFF Protein
规格 & 价格: cart
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Human MFF Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2q36.3 by HGNC 2q36.3 by Entrez Gene 2q36.3 by Ensembl
MFF Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer. Interacts with DNM1L.


功能:
Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.


亚细胞位置:
Mitochondrion outer membrane Single-pass type IV membrane protein Peroxisome Cytoplasmic vesicle Secretory vesicle Synaptic vesicle


该产品尚未在任何出版物中被引用。

[1].
"The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells."

[2].
"Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy."

[3].
"Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission."

[4].
"Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission."

[5].
"Potential use of TIA-1, MFF, microRNA-200a-3p, and microRNA-27 as a novel marker for hepatocellular carcinoma."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons."

[8].
"Substrate-Trapped Interactors of PHD3 and FIH Cluster in Distinct Signaling Pathways."

[9].
"Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family."

[10].
"Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity."
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