首页 > 重组蛋白 > Human METRNL Recombinant Protein

METRNL (基因名), Meteorin-like protein (蛋白名), METRL_HUMAN.

产品名称:

Human METRNL/ Meteorin-like protein Recombinant Protein
镍纹样蛋白

货号:

R7391h

商标:

EIAab^®

监管等级:

RUO

别名:

Subfatin

序列号:

Q641Q3

来源:

E.coli

种属:

Human

标签:

His

序列:

46-311aa

预估分子量:

29.26 kDa (monomer)

纯度:

Greater than 95% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

Cell Biology

规格 & 价格:

关注

Human METRNL Protein

邮箱 *

消息 *

Please 登录.

产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
反馈墙 (0)

R&D 技术数据

The PCR product of human METRNL gene was determined by 1% Agarose stained with EB.

Recombinant human METRNL protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 17q25.3 by HGNC 17q25.3 by Entrez Gene 17q25.3 by Ensembl

METRNL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

N/A

功能:

Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.

亚细胞位置:

Secreted

数据库链接

UniGene:

Hs.378821

STRING:

9606.ENSP00000315731

KEGG:

hsa:284207

MIM:

616241

Uniprot:

Q641Q3

相关产品

Mouse Metrnl ELISA Kit

Rat Metrnl ELISA Kit

Mouse Metrnl CLIA Kit

Rat Metrnl CLIA Kit

Mouse Metrnl Protein

序列长度:

311

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

311:

RGLNPCEVGT | D

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Subfatin is a novel adipokine and unlike Meteorin in adipose and brain expression."

(PMID: 24393292)

[2].

"Complete sequencing and characterization of 21,243 full-length human cDNAs."

(PMID: 14702039)

[3].

"METRNL decreases during adipogenesis and inhibits adipocyte differentiation leading to adipocyte hypertrophy in humans."

(PMID: 27748745)

[4].

"Architecture of the human interactome defines protein communities and disease networks."

(PMID: 28514442)

[5].

"Meteorin-Like Shows Unique Expression Pattern in Bone and Its Overexpression Inhibits Osteoblast Differentiation."

(PMID: 27716826)

[6].

"Adipocyte Metrnl Antagonizes Insulin Resistance Through PPARγ Signaling."

(PMID: 26307585)

[7].

"A human interactome in three quantitative dimensions organized by stoichiometries and abundances."

(PMID: 26496610)

[8].

"Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis."

(PMID: 24906147)

[9].

"Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)."

(PMID: 19199708)

[10].

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."

(PMID: 16625196)

[1].

人镍纹样蛋白(METRNL)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人镍纹样蛋白(METRNL)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人镍纹样蛋白(METRNL)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人镍纹样蛋白(METRNL)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人镍纹样蛋白(METRNL)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人镍纹样蛋白(METRNL)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人镍纹样蛋白(METRNL)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人镍纹样蛋白(METRNL)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

反馈墙

评论数 : 0

所有用户