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MAT1A (基因名), S-adenosylmethionine synthase isoform type-1 (蛋白名), METK1_HUMAN.
产品名称:

Human MAT1A/ S-adenosylmethionine synthase isoform type-1 Recombinant Protein
蛋氨酸腺苷转移酶1

货号:

R0246h

商标:
EIAab®
监管等级:
别名:

Methionine adenosyltransferase 1, Methionine adenosyltransferase I/III, MAT 1, MAT-I/III, AdoMet synthase 1, AMS1, MATA1

序列号:
Q00266
来源:
E.coli
种属:
Human
标签:
His
序列:
1-395aa
预估分子量:
43.45 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human MAT1A Protein
规格 & 价格: cart
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Human MAT1A Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10q22.3 by HGNC 10q22.3 by Entrez Gene 10q22.3 by Ensembl
MAT1A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homotetramer (MAT-I); dimer of dimers (PubMed:23425511). Homodimer (MAT-III).


功能:
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Demyelination of the brain is associated with methionine adenosyltransferase I/III deficiency."

[2].
"MAT1A variants are associated with hypertension, stroke, and markers of DNA damage and are modulated by plasma vitamin B-6 and folate."

[3].
"Methionine adenosyltransferase I/III deficiency: novel mutations and clinical variations."

[4].
"Dominant inheritance of isolated hypermethioninemia is associated with a mutation in the human methionine adenosyltransferase 1A gene."

[5].
"Molecular mechanisms of an inborn error of methionine pathway. Methionine adenosyltransferase deficiency."

[6].
"Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies."

[7].
"Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits."

[8].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."

[9].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[10].
"Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia."
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