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首页  >  重组蛋白  >  Human ACTN2 Recombinant Protein
ACTN2 (基因名), Alpha-actinin-2 (蛋白名), ACTN2_HUMAN.
产品名称:

Human ACTN2/ Alpha-actinin-2 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein

序列号:
P35609
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human ACTN2 Protein
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Human ACTN2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 1q43 by HGNC 1q43 by Entrez Gene 1q43 by Ensembl
ACTN2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer; antiparallel. Also forms heterodimers with ACTN3. Interacts with ADAM12, MYOZ1, MYOZ2 and MYOZ3. Interacts via its C-terminal region with the LDB3 PDZ domain. Interacts with XIRP2. Interacts with DST isoform 1 (via N-terminus). Interacts with PARVB. Interacts with SYNPO2.


功能:
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.


亚细胞位置:
Cytoplasm Myofibril Sarcomere Z line Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle.


该产品尚未在任何出版物中被引用。

[1].
"Cloning and characterization of two human skeletal muscle alpha-actinin genes located on chromosomes 1 and 11."

[2].
"Mutations in alpha-actinin-2 cause hypertrophic cardiomyopathy: a genome-wide analysis."

[3].
"alpha-actinin-3 and performance."

[4].
"ZASP: a new Z-band alternatively spliced PDZ-motif protein."

[5].
"Fine mapping and genomic structure of ACTN2, the human gene coding for the sarcomeric isoform of alpha-actinin-2, expressed in skeletal and cardiac muscle."

[6].
"Novel α-actinin 2 variant associated with familial hypertrophic cardiomyopathy and juvenile atrial arrhythmias: a massively parallel sequencing study."

[7].
"Exome sequencing identifies a mutation in the ACTN2 gene in a family with idiopathic ventricular fibrillation, left ventricular noncompaction, and sudden death."

[8].
"F-box and leucine-rich repeat protein 22 is a cardiac-enriched F-box protein that regulates sarcomeric protein turnover and is essential for maintenance of contractile function in vivo."

[9].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."

[10].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
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