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ACSM1 (基因名), Acyl-coenzyme A synthetase ACSM1, mitochondrial (蛋白名), ACSM1_HUMAN.
产品名称:

Human ACSM1/ Acyl-coenzyme A synthetase ACSM1, mitochondrial Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Acyl-CoA synthetase medium-chain family member 1, Benzoate--CoA ligase, Butyrate--CoA ligase 1, Butyryl-coenzyme A synthetase 1, Lipoate-activating enzyme, Middle-chain acyl-CoA synthetase 1, Xenobiotic/medium-chain fatty acid-CoA ligase HXM-B, BUCS1, LAE, MACS1

序列号:
Q08AH1
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ACSM1 Protein
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Human ACSM1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 16p12.3 by HGNC 16p12.3 by Entrez Gene 16p12.3 by Ensembl
ACSM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer.


功能:
Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (PubMed:10434065). Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate (PubMed:10434065). Also catalyzes the activation of lipoate to lipoyl-nucleoside monophosphate (By similarity). Activates lipoate with GTP at a 1000-fold higher rate than with ATP and activates both (R)- and (S)-lipoate to the respective lipoyl-GMP, with a preference for (R)-lipoate (By similarity).


亚细胞位置:
Mitochondrion matrix Mitochondrion


该产品尚未在任何出版物中被引用。

[1].
"Molecular identification and characterization of two medium-chain acyl-CoA synthetases, MACS1 and the Sa gene product."

[2].
"Two medium-chain acyl-coenzyme A synthetase genes, SAH and MACS1, are associated with plasma high-density lipoprotein cholesterol levels, but they are not associated with essential hypertension."

[3].
"Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort."

[4].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[5].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[6].
"Genomewide association for schizophrenia in the CATIE study: results of stage 1."

[7].
"15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma."

[8].
"An acyl-CoA synthetase gene family in chromosome 16p12 may contribute to multiple risk factors."

[9].
"Architecture of the human interactome defines protein communities and disease networks."

[10].
"Genetic association of ACSM1 variation with schizophrenia and major depressive disorder in the Han Chinese population."
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