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首页  >  重组蛋白  >  Human ACSL4 Recombinant Protein
ACSL4 (基因名), Long-chain-fatty-acid--CoA ligase 4 (蛋白名), ACSL4_HUMAN.
产品名称:

Human ACSL4/ Long-chain-fatty-acid--CoA ligase 4 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Arachidonate--CoA ligase, Long-chain acyl-CoA synthetase 4, LACS 4, ACS4, FACL4, LACS4

序列号:
O60488
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human ACSL4 Protein
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Human ACSL4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: Xq23 by HGNC Xq23 by Entrez Gene Xq23 by Ensembl
ACSL4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (PubMed:21242590).


亚细胞位置:
Mitochondrion outer membrane Single-pass type III membrane protein Peroxisome membrane Single-pass type III membrane protein Microsome membrane Single-pass type III membrane protein Endoplasmic reticulum membrane Single-pass type III membrane protein Cell membrane


该产品尚未在任何出版物中被引用。

[1].
"Association of a long-chain fatty acid-CoA ligase 4 gene polymorphism with depression and with enhanced niacin-induced dermal erythema."

[2].
"FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation."

[3].
"Fatty acid CoA ligase-4 gene polymorphism influences fatty acid metabolism in metabolic syndrome, but not in depression."

[4].
"No association between polymorphisms in the FACL4 (fatty acid-CoA ligase 4) gene and nonspecific mental retardation in Qin-Ba mountain region of China."

[5].
"Localization of a non-syndromic X-linked mental retardation gene (MRX80) to Xq22-q24."

[6].
"FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation."

[7].
"Cloning, expression, and chromosomal localization of human long-chain fatty acid-CoA ligase 4 (FACL4)."

[8].
"The effect of fatty acid-CoA ligase 4 on the growth of hepatic cancer cells."

[9].
"Regulation of cell growth by fatty acid-CoA ligase 4 in human hepatocellular carcinoma cells."

[10].
"Disruption of DMD and deletion of ACSL4 causing developmental delay, hypotonia, and multiple congenital anomalies."
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