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ACOT13 (基因名), Acyl-coenzyme A thioesterase 13 (蛋白名), ACO13_HUMAN.
产品名称:

Human ACOT13/ Acyl-coenzyme A thioesterase 13 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Thioesterase superfamily member 2, HT012, PNAS-27, Acyl-CoA thioesterase 13, THEM2

序列号:
Q9NPJ3
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ACOT13 Protein
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Human ACOT13 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 6p22.3 by HGNC 6p22.3 by Entrez Gene 6p22.3 by Ensembl
ACOT13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homotetramer.


功能:
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis.


亚细胞位置:
Cytoplasm Cytosol Mitochondrion Nucleus Cytoplasm Cytoskeleton Spindle During interphase, found both in the nucleus and in the cytoplasm. At mitosis, localizes to the spindle. Colocalizes with tubulin.


该产品尚未在任何出版物中被引用。

[1].
"The mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysis."

[2].
"Crystal structure of human thioesterase superfamily member 2."

[3].
"Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs."

[4].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[6].
"The DNA sequence and analysis of human chromosome 6."

[7].
"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning."

[8].
"RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination."

[9].
"Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children."

[10].
"Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function."
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