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CHRNE (基因名), Acetylcholine receptor subunit epsilon (蛋白名), ACHE_HUMAN.
产品名称:

Human CHRNE/ Acetylcholine receptor subunit epsilon Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

ACHRE

序列号:
Q04844
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human CHRNE Protein
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Human CHRNE Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 17p13.2 by HGNC 17p13.2 by Entrez Gene 17p13.2 by Ensembl
CHRNE Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.


功能:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Primary structure of the human muscle acetylcholine receptor. cDNA cloning of the gamma and epsilon subunits."

[2].
"Mutations Causing Slow-Channel Myasthenia Reveal That a Valine Ring in the Channel Pore of Muscle AChR is Optimized for Stabilizing Channel Gating."

[3].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[4].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[5].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."

[6].
"The CHRNE 1293insG founder mutation is a frequent cause of congenital myasthenia in North Africa."

[7].
"Lack of association between acetylcholine receptor epsilon polymorphisms and early-onset myasthenia gravis."

[8].
"Fundamental gating mechanism of nicotinic receptor channel revealed by mutation causing a congenital myasthenic syndrome."

[9].
"Immature end-plates and utrophin deficiency in congenital myasthenic syndrome caused by epsilon-AChR subunit truncating mutations."

[10].
"Congenital myasthenic syndromes due to heteroallelic nonsense/missense mutations in the acetylcholine receptor epsilon subunit gene: identification and functional characterization of six new mutations."
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