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首页  >  重组蛋白  >  Human CHRNA7 Recombinant Protein
CHRNA7 (基因名), Neuronal acetylcholine receptor subunit alpha-7 (蛋白名), ACHA7_HUMAN.
产品名称:

Human CHRNA7/ Neuronal acetylcholine receptor subunit alpha-7 Recombinant Protein
神经乙酰胆碱受体亚单位α-7

货号:

R9618h

商标:
EIAab®
监管等级:
别名:

NACHRA7

序列号:
P36544
来源:
E.coli
种属:
Human
标签:
His
序列:
169-270aa
预估分子量:
11.22 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
  • Human CHRNA7 Protein
  • Human CHRNA7 Protein
  • Human CHRNA7 Protein
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Human CHRNA7 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
The sequence analysis of human CHRNA7 protein including hydrophilcity, hydrophobicity and antigenicity.
Human CHRNA7 Protein
Recombinant human CHRNA7 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 15q13.3 by HGNC 15q13.3 by Entrez Gene 15q13.3 by Ensembl
CHRNA7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homopentamer (By similarity). Interacts with RIC3; which is required for proper folding and assembly (PubMed:15504725, PubMed:16120769). Interacts with LYPD6 (PubMed:27344019). Interacts with the alpha-conotoxin RgIA (By similarity). Interacts with alpha-conotoxins ImI and ImII (PubMed:15609996).


功能:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"APOE, ACT and CHRNA7 genes in the conversion from amnestic mild cognitive impairment to Alzheimer's disease."

[2].
"Association of the 5'-upstream regulatory region of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) with schizophrenia."

[3].
"Alpha7 nicotinic acetylcholine receptor gene and reduced risk of Alzheimer's disease."

[4].
"Genetic variation in the alpha 7 nicotinic acetylcholine receptor is associated with delusional symptoms in Alzheimer's disease."

[5].
"[The transmission disequilibrium analysis between neuronal nicotinic acetylcholine receptor alpha 7 subunit gene polymorphisms and schizophrenia]."
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