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首页  >  重组蛋白  >  Human CHRNA6 Recombinant Protein
CHRNA6 (基因名), Neuronal acetylcholine receptor subunit alpha-6 (蛋白名), ACHA6_HUMAN.
产品名称:

Human CHRNA6/ Neuronal acetylcholine receptor subunit alpha-6 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
序列号:
Q15825
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human CHRNA6 Protein
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Human CHRNA6 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 8p11.21 by HGNC 8p11.21 by Entrez Gene 8p11.21 by Ensembl
CHRNA6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Neuronal AChR seems to be composed of two different types of subunits: alpha and non-alpha (beta). Interacts with LYPD6 (PubMed:27344019).


功能:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits."

[2].
"Functional interaction between Lypd6 and nicotinic acetylcholine receptors."

[3].
"Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior."

[4].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."

[5].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[6].
"Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerstr?m test for nicotine dependence."

[7].
"Prenatal exposure to maternal cigarette smoking interacts with a polymorphism in the alpha6 nicotinic acetylcholine receptor gene to influence drug use and striatum volume in adolescence."

[8].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[9].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."

[10].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."
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