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CHRNA5 (基因名), Neuronal acetylcholine receptor subunit alpha-5 (蛋白名), ACHA5_HUMAN.
产品名称:

Human CHRNA5/ Neuronal acetylcholine receptor subunit alpha-5 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

NACHRA5

序列号:
P30532
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human CHRNA5 Protein
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Human CHRNA5 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 15q25.1 by HGNC 15q25.1 by Entrez Gene 15q25.1 by Ensembl
CHRNA5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Neuronal AChR seems to be composed of two different type of subunits: alpha and non-alpha (beta). Interacts with LYPD6 (PubMed:27344019).


功能:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans."

[2].
"Smoking cessation and variations in nicotinic acetylcholine receptor subunits alpha-5, alpha-3, and beta-4 genes."

[3].
"Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk."

[4].
"Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence."

[5].
"Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function."

[6].
"Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1."

[7].
"A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25."

[8].
"A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence."

[9].
"Variants in nicotinic receptors and risk for nicotine dependence."

[10].
"Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking."
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