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ACER3 (基因名), Alkaline ceramidase 3 (蛋白名), ACER3_HUMAN.
产品名称:

Human ACER3/ Alkaline ceramidase 3 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Alkaline dihydroceramidase SB89, Alkaline phytoceramidase, aPHC, AlkCDase 3, APHC, PHCA

序列号:
Q9NUN7
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ACER3 Protein
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Human ACER3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 11q13.5 by HGNC 11q13.5 by Entrez Gene 11q13.5 by Ensembl
ACER3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.


亚细胞位置:
Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide."

[2].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[3].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[4].
"Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging."

[5].
"Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy."

[9].
"ACER3 supports development of acute myeloid leukemia."

[10].
"Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis."
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