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ACADSB (基因名), Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (蛋白名), ACDSB_HUMAN.
产品名称:

Human ACADSB/ Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial Recombinant Protein
线粒体,短/支链特异性酰基辅酶a脱氢酶

货号:

R12556h

商标:
EIAab®
监管等级:
别名:

2-methyl branched chain acyl-CoA dehydrogenase, 2-methylbutyryl-coenzyme A dehydrogenase, 2-MEBCAD, 2-methylbutyryl-CoA dehydrogenase, SBCAD

序列号:
P45954
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human ACADSB Protein
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Human ACADSB Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10q26.13 by HGNC 10q26.13 by Entrez Gene 10q26.13 by Ensembl
ACADSB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homotetramer.


功能:
Has greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl-CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.


亚细胞位置:
Mitochondrion matrix


该产品尚未在任何出版物中被引用。

[1].
"Short/branched-chain acyl-CoA dehydrogenase deficiency due to an IVS3+3A>G mutation that causes exon skipping."

[2].
"Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism."

[3].
"Localization of short/branched chain acyl-CoA dehydrogenase (ACADSB) to human chromosome 10."

[4].
"Isolation and expression of a cDNA encoding the precursor for a novel member (ACADSB) of the acyl-CoA dehydrogenase gene family."

[5].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[6].
"Association of genetic polymorphisms of ACADSB and COMT with human hypertension."

[7].
"A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease."

[8].
"Inborn errors of isoleucine degradation: a review."

[9].
"2-ethylhydracrylic aciduria in short/branched-chain acyl-CoA dehydrogenase deficiency: application to diagnosis and implications for the R-pathway of isoleucine oxidation."

[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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