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首页  >  重组蛋白  >  Rat Accn3 Recombinant Protein
Accn3 (基因名), Amiloride-sensitive cation channel 3 (蛋白名), ACCN3_RAT.
产品名称:

Rat Accn3/ Amiloride-sensitive cation channel 3 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Acid-sensing ion channel 3, Dorsal root ASIC, ASIC3, DRASIC, Asic3, Drasic

序列号:
O35240
来源:
E.coli
种属:
Rat
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Rat Accn3 Protein
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Rat Accn3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
Homotrimer or heterotrimer with other ASIC proteins (By similarity). Interacts with STOM, LIN7B, MAGI1 and GOPC (By similarity). Interacts with DLG4 and ACCN1.


功能:
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.


亚细胞位置:
Cytoplasm Cell membrane Multi-pass membrane protein In part cytoplasmic in cochlea cells (By similarity). Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4.


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