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首页  >  重组蛋白  >  Human DBI Recombinant Protein
DBI (基因名), Acyl-CoA-binding protein (蛋白名), ACBP_HUMAN.
产品名称:

Human DBI/ Acyl-CoA-binding protein Recombinant Protein

货号:

R15615h

商标:
EIAab®
监管等级:
别名:

Diazepam-binding inhibitor, Endozepine, DBI, EP, ACBP

序列号:
P07108
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human DBI Protein
规格 & 价格: cart
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Human DBI Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2q14.2 by HGNC 2q14.2 by Entrez Gene 2q14.2 by Ensembl
DBI Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer.


功能:
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.


亚细胞位置:
Endoplasmic reticulum Golgi apparatus Golgi localization is dependent on ligand binding (PubMed:17953517).


该产品尚未在任何出版物中被引用。

[1].
"High resolution crystal structures of unliganded and liganded human liver ACBP reveal a new mode of binding for the acyl-CoA ligand."

[2].
"Association of acyl-CoA-binding protein (ACBP) single nucleotide polymorphisms and type 2 diabetes in two German study populations."

[3].
"Identification of new acyl-CoA binding protein transcripts in human and mouse."

[4].
"Specific regulation of low-abundance transcript variants encoding human Acyl-CoA binding protein (ACBP) isoforms."

[5].
"Identification of a novel human Acyl-CoA binding protein isoform with a unique C-terminal domain."

[6].
"ACBP knockdown leads to down-regulation of genes encoding rate-limiting enzymes in cholesterol and fatty acid metabolism."

[7].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[8].
"Genetical genomic determinants of alcohol consumption in rats and humans."

[9].
"Transcriptional regulation of HMG-CoA synthase and HMG-CoA reductase genes by human ACBP."

[10].
"Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks."
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