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首页  >  重组蛋白  >  Human ACAP1 Recombinant Protein
ACAP1 (基因名), Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (蛋白名), ACAP1_HUMAN.
产品名称:

Human ACAP1/ Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Centaurin-beta-1, Cnt-b1, CENTB1, KIAA0050

序列号:
Q15027
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ACAP1 Protein
×
Human ACAP1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 17p13.1 by HGNC 17p13.1 by Entrez Gene 17p13.1 by Ensembl
ACAP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Banana-shaped homodimer laterally assembling into tetramers, the tetramers further pack helically onto the membrane. Interacts with GTP-bound ARF6. Interacts with third cytoplasmic loop of SLC2A4/GLUT4. Interacts with CLTC. Interacts with GULP1. Forms a complex with GDP-bound ARF6 and GULP1. Interacts with ITGB1; required for ITGB1 recycling.


功能:
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.


亚细胞位置:
Recycling endosome membrane Peripheral membrane protein Cytoplasmic side


该产品尚未在任何出版物中被引用。

[1].
"ACAPs are arf6 GTPase-activating proteins that function in the cell periphery."

[2].
"An ACAP1-containing clathrin coat complex for endocytic recycling."

[3].
"Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation."

[4].
"Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry."

[5].
"Mechanistic insights into regulated cargo binding by ACAP1 protein."

[6].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[7].
"Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study."

[8].
"Centaurin beta1 down-regulates nucleotide-binding oligomerization domains 1- and 2-dependent NF-kappaB activation."

[9].
"Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration."

[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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