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首页  >  重组蛋白  >  Human ACACB Recombinant Protein
ACACB (基因名), Acetyl-CoA carboxylase 2 (蛋白名), ACACB_HUMAN.
产品名称:

Human ACACB/ Acetyl-CoA carboxylase 2 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

ACC-beta, ACC2, ACCB

序列号:
O00763
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ACACB Protein
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Human ACACB Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


基因位点
Cytogenetic band: 12q24.11 by HGNC 12q24.11 by Entrez Gene 12q24.11 by Ensembl
ACACB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.


功能:
Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage (By similarity). May play a role in regulation of mitochondrial fatty acid oxidation through malonyl-CoA-dependent inhibition of carnitine palmitoyltransferase 1.


亚细胞位置:
Mitochondrion Nucleus Endomembrane system May associate with membranes.


该产品尚未在任何出版物中被引用。

[1].
"A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes."

[2].
"ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected]."

[3].
"Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels."

[4].
"Exploring genetic variations that may be associated with the direct effects of some antipsychotics on lipid levels."

[5].
"Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes."
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