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首页  >  重组蛋白  >  Human ACACA Recombinant Protein
ACACA (基因名), Acetyl-CoA carboxylase 1 (蛋白名), ACACA_HUMAN.
产品名称:

Human ACACA/ Acetyl-CoA carboxylase 1 Recombinant Protein
乙酰辅酶A羧化酶1

货号:

R1284h

商标:
EIAab®
监管等级:
别名:

Acetyl-Coenzyme A carboxylase alpha, ACC-alpha, ACC1, ACAC, ACC1, ACCA

序列号:
Q13085
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Metabolism
Human ACACA Protein
规格 & 价格: cart
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Human ACACA Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 17q12 by HGNC 17q12 by Entrez Gene 17q12 by Ensembl
ACACA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer, homodimer, and homotetramer (PubMed:20952656). Can form filamentous polymers (PubMed:20457939, PubMed:20952656). Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis (PubMed:12360400, PubMed:16326698). Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity (PubMed:20457939).


功能:
Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA, a key metabolite in the fatty acid synthetic (PubMed:20952656, PubMed:20457939). Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (PubMed:20952656, PubMed:20457939).


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility."

[2].
"Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels."

[3].
"Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition."

[4].
"BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase."

[5].
"Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes."

[6].
"Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility."

[7].
"Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels."

[8].
"Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition."

[9].
"BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase."

[10].
"Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes."
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