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首页  >  重组蛋白  >  Mouse Abhd12 Recombinant Protein
Abhd12 (基因名), Lysophosphatidylserine lipase ABHD12 (蛋白名), ABD12_MOUSE.
产品名称:

Mouse Abhd12/ Lysophosphatidylserine lipase ABHD12 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

2-arachidonoylglycerol hydrolase ABHD12, Abhydrolase domain-containing protein 12, Monoacylglycerol lipase ABHD12, Oxidized phosphatidylserine lipase ABHD12

序列号:
Q99LR1
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Abhd12 Protein
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Mouse Abhd12 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS


通用注释


亚单元:
N/A


功能:
Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (PubMed:23297193, PubMed:25580854, PubMed:30420694). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (PubMed:23297193). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal (PubMed:30643283). Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways (PubMed:18096503). Has a strong preference for very-long-chain lipid substrates; substrate specificity is likely due to improved catalysis and not improved substrate binding (PubMed:30237167).


亚细胞位置:
Endoplasmic reticulum membrane Single-pass membrane protein Mitochondrion


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