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ABCG8 (基因名), ATP-binding cassette sub-family G member 8 (蛋白名), ABCG8_HUMAN.
产品名称:

Human ABCG8/ ATP-binding cassette sub-family G member 8 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Sterolin-2

序列号:
Q9H221
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Human ABCG8 Protein
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Human ABCG8 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 2p21 by HGNC 2p21 by Entrez Gene 2p21 by Ensembl
ABCG8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
May form heterodimers with ABCG5 or be tightly coupled to ABCG5 along a pathway regulating diatery-sterol absorption and excretion.


功能:
Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.


亚细胞位置:
Membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Increased gallstone risk in humans conferred by common variant of hepatic ATP-binding cassette transporter for cholesterol."

[2].
"Genetic variations at ABCG5/G8 genes modulate plasma lipids concentrations in patients with familial hypercholesterolemia."

[3].
"Common sequence variants in pharmacodynamic and pharmacokinetic pathway-related genes conferring LDL cholesterol response to statins."

[4].
"ABCG8 gene polymorphisms, plasma cholesterol concentrations, and risk of cardiovascular disease in familial hypercholesterolemia."

[5].
"Long-term consumption of plant stanol and sterol esters, vascular function and genetic regulation."

[6].
"The metabolism of plant sterols is disturbed in postmenopausal women with coronary artery disease."

[7].
"Significant association of ABCG5 604Q and ABCG8 D19H polymorphisms with gallstone disease."

[8].
"Significant association of ABCG8:D19H gene polymorphism with hypercholesterolemia and insulin resistance."

[9].
"Association between non-responsiveness to plant sterol intervention and polymorphisms in cholesterol metabolism genes: a case-control study."

[10].
"Single nucleotide polymorphisms in ABCG5 and ABCG8 genes in Chilean subjects with polygenic hypercholesterolemia and controls."
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