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ABCD4 (基因名), ATP-binding cassette sub-family D member 4 (蛋白名), ABCD4_HUMAN.
产品名称:

Human ABCD4/ ATP-binding cassette sub-family D member 4 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

PMP70-related protein, Peroxisomal membrane protein 1-like, Peroxisomal membrane protein 69, P70R, PXMP1-L, PMP69, PXMP1L

序列号:
O14678
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ABCD4 Protein
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Human ABCD4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 14q24.3 by HGNC 14q24.3 by Entrez Gene 14q24.3 by Ensembl
ABCD4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer or heterodimer.


功能:
May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm.


亚细胞位置:
Peroxisome membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Primary structure of human PMP69, a putative peroxisomal ABC-transporter."

[2].
"Genomic organization and chromosomal localization of the human peroxisomal membrane protein-1-like protein (PXMP1-L) gene encoding a peroxisomal ABC transporter."

[3].
"Identification of a fourth half ABC transporter in the human peroxisomal membrane."

[4].
"Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism."

[5].
"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."

[6].
"Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy."

[7].
"Targeting of the human adrenoleukodystrophy protein to the peroxisomal membrane by an internal region containing a highly conserved motif."

[8].
"Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8."

[9].
"Architecture of the human interactome defines protein communities and disease networks."

[10].
"Clinical or ATPase domain mutations in ABCD4 disrupt the interaction between the vitamin B12-trafficking proteins ABCD4 and LMBD1."
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